Miyerkules, Nobyembre 14, 2012
Schizophrenia Gene Networks Found
The computational analysis uncovered two vast genetic networks involved in schizophrenia, including one (pictured) that is related to a previously discovered genetic network involved in autism.
A new study by researchers at Columbia University Medical Center identifies affected gene networks and provides insight into the molecular causes of the disease.
The paper was published today in the online edition of the journal Nature Neuroscience.
Using an unbiased collection of hundreds of mutations associated with schizophrenia,They removed the majority of the bolts but not the locking Wheel nut, that's why I managed to get so far the Columbia researchers applied a sophisticated computational approach to uncover hidden relationships among seemingly unrelated genes.
The analysis revealed that many of the genes mutated in schizophrenia are organized into two main networks, which take part in a few key processes, including axon guidance, synapse function, neuron mobility, and chromosomal modification.www.globalmetaltins.com is a professional metal packaging manufacturers,Welcome.An Optic circulator is a special fiber-optic component that can be used to separate optical signals that travel in opposite directions in an optical fiber, analogous to the operation of an electronic circulator.
The study also uncovered an intriguing connection between schizophrenia and autism. “If we hadn’t known that these were two different diseases, and had put all the mutations into a single analysis, it would have come up with very similar networks,A female road sweeper was unfairly driven out by Merton Council after repeatedly complaining about sub-standard working conditions and discrimination, a tribunal has ruled.” said the study’s senior author, Dennis Vitkup, PhD, associate professor in the Department of Biomedical Informatics,The convenient way to order Tuner wheel lug nut, lug nuts and valve stems the Center for Computational Biology and Bioinformatics, and the Columbia Initiative in Systems Biology at Columbia University Medical Center. “It shows how closely the autism and schizophrenia genetic networks are intertwined,” he added.
Although it will take time to translate the findings into practical treatments, the study provides insight into the molecular causes of schizophrenia. It also suggests that mutations associated with schizophrenia, autism, and probably many other psychiatric disorders, are likely to converge on a set of interrelated molecular processes.
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